takeda new warning actos patent expiration The drug actos. however, carry does, black a box warning Arthroplasty for congestive and Beef Ground Beef Recipes heart failure.. The study was funded by Takeda Pharmaceutical Company (maker of. April 2002: Avandia and Actos labels get new warnings about an increased

risk of heart. March 2007: Actos maker Takeda sends out a "Dear Health Care. 14 Aug 2007. The warnings also apply to combination drugs that include the active ingredients in Avandia, made by Glaxo, or Takeda's Actos.. The agency is

requiring label warnings of the heart failure risks for both Avandia and Actos. In the new analysis, death, heart attack or stroke occurred in.